how to startflour millbusiness? cost & steps

how to startflour millbusiness? cost & steps

Although there are many flour milling plants in the market, but the high demand for various flours makes it still profitable to start flour milling business through setting up small scale or medium scale flour mill factory.

Many people are interested in starting flour mill business.However, they have no ideas about the detailed steps and perspective cost of flour mill factory setup. And they are also curious about how much money can a flour mill, like a small scale, make per year. Here, ABC Machinery offers the information you may be needed, like wheat flour mill business plan. (You may also like:Flour Mill Plant Cost>>)

Generally, flour milling business has two types small scale or large scale. Choosing small scale or large scale should fully take your specific conditions into consideration. Here we will analyze the small scale flour mill and large scale flour mill plant for your consideration.

Firstly, the small scale flour mill machinery requires small amount of money, but the profit margin is relatively small. It works greatly in two models, one is to charge a certain amount for milling grains, the other is to produce flour mill. So, small scale flour mill business is flexible, you can adjust your production based on the market needs. In addition, the whole operations are relatively easy and simple, so almost all the adult can use it.

It is inevitable that large scale flour mill project requires heavy investment since the complicated flour milling process and advanced flour milling machinery. However, the profits are decent in most cases since there are large demand of wheat flour around the world, especially in some regions, such as India, Egypt, Algeria, Italy, Brazil, etc. Large scale flour mill plant can achieve automatic and continuous flour production, from raw materials to packaged flour.

The cost for a flour mill factory varies a lot due to the different production capacity. If you are going to set up a small scale factory flour mill, the cost will be a much cheaper than medium scale or large scale flour mill plant. Setting up flour mill plant may require large amount, so if you doesnt have enough money but wont want miss the profitable endeavors, you can search helps of bank loans or just to find out a reliable partner who is also enthusiastic about the flour milling business.

Typically, the F6FC mini flour mill machine will cost$2,500 ~ $3,000. The M6FX mini flour mill factory will cost$3,500 ~ $5,000. However, for the large scale flour mill factory, the cost definitely high. For example, the large scale flour mill plant equiped with automatic wheat mill machinery may cost$19,000 ~$1,448,000.But, this price is just for a references, the exact cos of the flour mill factory plant should based on the exact conditions and equipment selections!

If you are interested in starting your own wheat/atta flour mill business, or other grain flour business, like cassava flour milling, please contact us for FREE quotation on both small scale or large scale flour mill machinery.

Any business will need financial support before starting. How much money is required to have theflour milling machine? Is it needed to take out loans or just put all your money into this business. For the estimate amount, it is better to have a better understanding about local market as well as global market of profit in flour mill business. (Read more:Get the Policy Loan for Your Business>>)

A right factory location is very important for the flour milling business. The right factory location should have convenient transportation that is easily for the access of raw materials and delivery and shipping of final packed flour. After the location is decided, it it time to get out the covering area of theflour processing plant. In general, a completeflour mill plant layoutshould include thearea for storage of raw materials,area for flour milling machines,area for flour packaging.

Getting the licence from the government or registering your factory in local administration is also important for thesuccess of the flour milling business. It is the basic requirements for a flour milling factory to ensure every policy and flour production process are compliant with the local regulation and legislation.

When above mentioned conditions are ready, it is time to think about how and where to get theflour milling machinery.The selection offlour milling machinesare closely connected with the capacity, the investment cost, the flour milling process, the raw materials and more. Therefore, it cant be done overnight. It needs to take time to choose the most reliable flour milling machinery supplier, which can help to avoid many unexpected problems in the installation and operation of the flour milling factory and lower the cost of machinery purchases. (Read more:Wheat Flour Machine Suppliers>>)

For most flour mill factory, there should be have several operators or workers forflour production.The systematic training and safety education for the workers and operators are very important one the flour mill factory starts running. They not only should to have a good command of the equipment and machinery, but also need to know how to flour ingredients additions. Mostfour mill machinery supplierwill offer the training plan and course for their customers to help them quickly enters the flour industry and avoid many typical operational mistakes.

How to make the final produced flour to the direct customers is also a hard task for flour milling factory investors. If the competition of local flour market is low, then dont worry, the selling of final flour products will be very good. Some markets, such Nigeria, India, Pakistan, Uganda, Chile, Australia, Algeria, Ethiopia and more, are very hot for start flour milling business since the high demand and low competition. (Read more:Flour Mill Project Built by ABC Machinery>>)

When you are going to start flour mill business by setting up a flour mill factory, you can have a reference of the above mentioned tips and steps for a complete and viable flour milling business plan. ABC Machinery can offercustom-made flour mill business planto easily get start flour milling business. If you still have many confusions, please just contact us for more detailed information, we have built many flour mill projects all over the world. We do believe, some of our experiences are what you want!

buskirk engineering | american made pellet mills

buskirk engineering | american made pellet mills

Buskirk Engineering. The industry leader in manufacturing American Made Flat Die Pellet Mills. We specialize in Turnkey System Solutions, as well as engineering and design services for a variety of different applications.

Buskirk Engineering of North America has been a leader in the biomass densification industry for over a decade. We pride ourselves on building high quality flat die pellet mills, ancillary equipment, and turnkey system solutions. Being manufactured in the heart of the Midwest, our High Torque/Low RPM principle designed pellet mill is one of a kind, constructed with the highest quality steels for absolute performance and durability. Always striving to improve, we work closely with clients understanding their needs, offering affordable, reliable solutions. Why wait until tomorrow? Lets get started on your project, today.

routes of administration and dosage forms - pharmacology - merck veterinary manual

routes of administration and dosage forms - pharmacology - merck veterinary manual

A diverse range of dosage forms and delivery systems has been developed to provide for the care and welfare of animals. The development of dosage forms draws on the discipline of biopharmaceutics, which integrates an understanding of formulations, dissolution, stability, and controlled release (pharmaceutics); absorption, distribution, metabolism, and excretion (pharmacokinetics, PK); concentration-effect relationships and drug-receptor interactions (pharmacodynamics, PD); and treatment of the disease state (therapeutics). Formulation of a dosage form typically involves combining an active ingredient and one or more excipients; the resultant dosage form determines the route of administration and the clinical efficacy and safety of the drug. Optimization of drug doses is also critical to achieving clinical efficacy and safety. Increasingly, a PK/PD model that describes the drug response is the basis of dose optimization. The PK and PD phases are linked by the premise that free drug in the systemic circulation is in equilibrium with the receptors. The PD phase generally involves interaction of the drug with a receptor, which triggers post-receptor events and eventually leads to a drug effect (see Drug Concentration and Effect).

Drug delivery strategies for veterinary formulations are complicated by the diversity of species and breeds treated, the wide range in body sizes, different husbandry practices, seasonal variations, cost constraints associated with the value of the animal being treated, the persistence of residues in food and fiber (see Chemical Residues in Food and Fiber), and the level of convenience, among other factors. Innovative solutions have been developed to meet many of these challenges (eg, the convenient dosing option offered by topical spot-on formulations to treat external and internal parasites on dogs and cats, the microencapsulation of NSAIDs as a way to mask taste when these agents are added to the rations of horses). The anatomy of the GI tract of ruminants presents unique opportunities for controlled-release drug delivery systems, and many such systems are on the market. For example, controlled-release boluses have been developed to deliver antimicrobials, anthelmintics, production enhancers, nutritional supplements, and other drugs.

The oral route of administration is frequently used in both companion and food animals. In dogs and cats, tablets, capsules, solutions, and suspensions are administered orally; pastes are also applied to the forelimbs of cats from which they are licked and ingested. In horses, solutions and suspensions are administered by nasogastric tubes, pastes are applied to the tongue, and granules are added to rations for ingestion. The oral route of administration is the most widely used in cattle, pigs, and poultry. Formulations range from premixes and drinking water additives to licks, pastes, drenches, tablets, capsules, and boluses. Oral dosage forms are usually intended for systemic effects resulting from drug absorption from the GI tract; however, some oral suspensions, eg, kaolin, are intended to produce local effects, and these are not absorbed. Disadvantages of the oral route of administration include the relatively slow onset of action, the possibilities of irregular absorption, the destruction of acid-labile drugs in the stomach, and the unsuitability of this route for many high-molecular-weight drugs. Oral dosage forms require careful pharmaceutical formulation.

Oral dosage forms comprise liquids (solutions, suspensions, emulsions, elixirs, and syrups), semisolids (pastes), and solids (tablets, capsules, powders, granules, premixes, and medicated blocks). These dosage forms together with examples of modified-release delivery systems for ruminants are discussed below.

A solution is a mixture of two or more components that form a single phase that is homogeneous down to the molecular level. Solutions offer several advantages over other dosage forms. Compared with solid dosage forms, solutions are absorbed faster and generally cause less irritation of the GI mucosa. Moreover, phase separation on storage is not a concern with solutions, as it may be for suspensions and emulsions. The disadvantages of solutions include susceptibility to microbial contamination and the hydrolysis in aqueous solution of susceptible active ingredients. In addition, the taste of some drugs is more unpleasant when in solution. A range of additives is used in the formulation of oral solutions, including buffers, flavors, antioxidants, and preservatives. Oral solutions provide a convenient means of drug administration to neonates and young animals.

A suspension is a coarse dispersion of insoluble drug particles, generally with a diameter >1 m, in a liquid (usually aqueous) medium. Suspensions are useful to administer insoluble or poorly soluble drugs or when the presence of a finely divided form of the material in the GItract is required. An example of the latter is the treatment of frothy bloat with dimethyl polysiloxanes, which relies on a dispersion of finely divided silica in the forestomach of ruminants. The taste of most drugs is less noticeable in suspension than in solution, because the drug is less soluble in suspension. Particle size is an important determinant of the dissolution rate and bioavailability of drugs in suspension. In addition to the excipients described above for solutions, suspensions include surfactants and thickening agents. Surfactants wet the solid particles, thereby ensuring the particles disperse readily throughout the liquid. Thickening agents reduce the rate atwhich particles settle to the bottom of the container. Some settling is acceptable, provided the sediment can be readily dispersedwhen the container is shaken. Redispersion of the suspension may not be achievable if the sediment has packed closely to form a hard mass, a process known as "caking."

An emulsion is a system consisting of twoimmiscible liquid phases, one of which is dispersed throughout the other in the form of fine droplets; droplet diameter generally ranges from 0.1100 m. The two phases of an emulsion are known as the dispersed phase and the continuous phase. Emulsions are inherently unstable and are stabilized through the use of an emulsifying agent, which prevents coalescence of the dispersed droplets. Creaming, as occurs with milk, also occurs with pharmaceutical emulsions. However, it is not a serious problem because a uniform dispersion returns upon shaking. Creaming is, nonetheless, undesirable because it is associated with an increased likelihood of the droplets coalescing and the emulsion breaking. Other additives include buffers, antioxidants, and preservatives. Emulsions for oral administration are usually oil (the active ingredient) in water, and they facilitate the administration of oily substances such as castor oil or liquid paraffin in a more palatable form.

An elixir is a sweetened, usually hydroalcoholic solution of a bitter or nauseous drug intended for oral administration. The hydroalcoholic character of elixirs allows, within limits, both water-soluble and alcohol-soluble medicinal substances to be maintained in solution. The proportion of alcohol in elixirs varies widely, a characteristic used to advantage to solubilize medicinal agents. If the active ingredient is sensitive to moisture, it may be formulated as a flavored powder or granulation and reconstituted in water immediately before oral administration. Nonmedicated elixirs are used as the vehicles for pharmaceutical formulations.

A syrup is a concentrated aqueous solution of sugar or a sugar substitute with or without flavoring agents and a water-soluble drug. Sucrose is the most frequently used sugar, and syrups usually contain 60%80%. Syrups may also contain cosolvents, solubilizing agents, thickeners, or stabilizers. Nonmedicated syrups are used as vehicles for water-soluble drugs.

A paste is a two-component semisolid in which drug is dispersed as a powder in an aqueous or fatty base. The particle size of the active ingredient in pastes can be as large as 100 m. The vehicle containing the drug may be water; a polyhydroxy liquid such as glycerin, propylene glycol, or polyethylene glycol; a vegetable oil; or a mineral oil. Other formulation excipients include thickening agents, cosolvents, adsorbents, humectants, and preservatives. The thickening agent may be a naturally occurring material such as acacia or tragacanth, or a synthetic or chemically modified derivative such as xanthum gum or hydroxypropylmethyl cellulose. The degree of cohesiveness, plasticity, and syringeability of pastes is attributed to the thickening agent. It may be necessary to include a cosolvent to increase the solubility of the drug. Syneresis of pastes is a form of instability in which the solid and liquid components of the formulation separate over time; it is prevented by including an adsorbent such as microcrystalline cellulose. A humectant (eg, glycerin or propylene glycol) is used to prevent the paste that collects at the nozzle of the dispenser from forming a hard crust. Microbial growth in the formulation is inhibited using a preservative. It is critical that pastes have a pleasant taste or are tasteless and are able to be used throughout a wide temperature range. Pastes are a popular dosage form to treat cats and horses and can be easily and safely administered by owners.

A tablet consists of one or more active ingredients and numerous excipients and may be a conventional tablet that is swallowed whole, a chewable tablet, or a modified-release tablet (these are commonly referred to as modified-release boluses when the unit size is large). Conventional and chewable tablets are used to administer drugs to dogs and cats, whereas modified-release boluses are administered to cattle, sheep, and goats. The physical and chemical stability of tablets is generally better than that of liquid dosage forms. The main disadvantages of tablets are a relatively slow onset of action because of the need to pass into the intestine and then undergo disintegration and dissolution before absorption across the gut wall, the low bioavailability of poorly water-soluble drugs or poorly absorbed drugs, and the local irritation of the GI mucosa that some drugs may cause.

A capsule is an oral dosage form usually made from gelatin and filled with an active ingredient and excipients. Two common capsule types are available: hard gelatin capsules for solid-fill formulations, and soft gelatin capsules for liquid-fill or semisolid-fill formulations. Soft gelatin capsules are suitable to formulate poorly water-soluble drugs because they afford good drug release and absorption by the GI tract. Gelatin capsules are frequently more expensive than tablets but have some advantages. For example, particle size is rarely altered during capsule manufacture, and capsules mask the taste and odor of the active ingredient and protect photolabile ingredients.

A powder is a formulation in which a drug powder is mixed with other powdered excipients to produce a final product for oral administration. Powders have better chemical stability than liquids and dissolve faster than tablets or capsules because disintegrationis not an issue. This translates into faster absorption for those drugs characterized by dissolution rate-limited absorption. Unpleasant tastes can be more pronounced with powders than with other dosage forms and can be a particular concern with in-feed powders, leading to variable ingestion of the desired dose. Moreover, sick animals often eat less and are therefore not amenable to treatment with in-feed powder formulations. Drug powders are principally used prophylactically in feed or formulated as a soluble powder for addition to drinking water or milk replacer. Powders have also been formulated with emulsifying agents to facilitate their administration as liquid drenches.

A granule is a dosage form consisting of powder particles that have been aggregated to form a larger mass, usually 24 mm in diameter. Granulation overcomes segregation of the different particle sizes during storage and/or dose administration, the latterbeing a potential source of inaccurate dosing. Granules and powders generally behave similarly; however, granules must deaggregate before dissolution and absorption.

A premix is a solid dosage form in which an active ingredient, such as a coccidiostat, production enhancer, or nutritional supplement, is formulated with excipients. Premix products are mixed homogeneously with feed at rates (when expressed on an active ingredient basis) that range from a few milligrams to ~200 g/ton of feed. They are administered to poultry, pigs, and ruminants. The density, particle size, and geometry of the premix particles should match as closely as possible those of the feed in which the premix will be incorporated to facilitate uniform mixing. Issues such as instability, electrostatic charge, and hygroscopicity must also be addressed. The excipients present in premix formulations include carriers, liquid binders, diluents, anticaking agents, and antidust agents. Carriers, such as wheat middlings, soybean mill run, and rice hulls, bind active ingredients to their surfaces and are important in attaining uniform mixing of the active ingredient. A liquid binding agent, such as a vegetable oil, should be included in the formulation whenever a carrier is used. Diluents increase the bulk of premix formulations, but unlike carriers, they do not bind the active ingredients. Examples of diluents include ground limestone, dicalcium phosphate, dextrose, and kaolin. Caking in a premix formulation may be caused by hygroscopic ingredients and is addressed by adding small amounts of anticaking agents such as calcium silicate, silicon dioxide, and hydrophobic starch. The dust associated with powdered premix formulations can have serious implications for both operator safety and economic losses and is reduced by including a vegetable oil or light mineral oil in the formulation. An alternative approach to overcoming dust is to granulate the premix formulation.

A medicated block is a compressed feed material that contains an active ingredient, such as a drug, anthelmintic, surfactant (for bloat prevention), or a nutritional supplement, and is commonly packaged in a cardboard box to feed to livestock. Ruminants typically have free access to the medicated block over several days, and variable consumption may be problematic. This concern is addressed by ensuring the active ingredient is nontoxic, stable, palatable, and preferably of low solubility. In addition, excipients in the formulation modulate consumption by altering the palatability and/or the hardness of the medicated block. For example, molasses increases palatability, and sodium chloride decreases it. Additionally, the incorporation of a binder such as lignin sulfonate in blocks manufactured by compression, or magnesium oxide in blocks manufactured by chemical reaction, increases hardness. The hygroscopic nature of molasses in a formulation may also impact the hardness of medicated blocks and is addressed by using appropriate packaging.

Several modified-release delivery systems have been developed that take advantage of the unique anatomy of the ruminant forestomach. Prominent among these systems are intraruminal boluses, which contain a range of active ingredients including parasiticides, nutritional supplements, antibloat agents, and production enhancers. They are administered using a balling gun. Most of the commercially available intraruminal boluses are continuous-release devices that rely on erosion, diffusion from a reservoir, dissolution of a dispersed matrix, or an osmotic driver to release the active ingredient. The pay-out period for intraruminal boluses is commonly >100 days. Regurgitation during rumination is prevented by the bolus having a density of ~3 g/cm3 or a variable geometry.

Other types of oral modified-release delivery systems are also available for ruminants. For example, sustained-release boluses that deliver sulfonamides throughout a period of ~72 hr are available to treat cattle. In addition, sustained-release boluses containing methoprene or diflubenzuron areapproved for the control of manure-breeding flies in cattle.

The intraruminal devices to supplement ruminants with selenium, cobalt, or copper include soluble glass boluses andintraruminal pellets. Boluses of soluble glass containing selenium, cobalt, and copper are available for cattle and sheep. Because glass is susceptible to sudden changes in temperature, glass boluses should be at least 1520C at the time of administration to avoid fracturing, which in turn may lead to regurgitation. Glass boluses are designed to dissolve in ruminal fluids, thereby releasing the incorporated elements. The composition of the glass determines the solubility of the bolus, with an increase in the ratio of monovalent to divalent cations resulting in an increase in solubility. The glass boluses are retained in the rumen for up to 9 mo.

Intraruminal pellets containing selenium or cobalt are available for sheep. Selenium or cobalt is released throughout a period of ~3 yr from the pellet matrix, which consists of compressed iron grit. When selenium or cobalt intraruminal pellets are administered alone, a grinder is usually coadministered to prevent the formation of calcium phosphate coatings on the surface of the pellets.

Copper capsules, which contain oxidized copper wire particles encapsulated in gelatin, are available for adult sheep and goats. After oral administration, the gelatin capsule dissolves in the rumen and releases the particles of copper oxide. The particles progress to the abomasum, where some are trapped in the mucosal folds and release copper.

A drug given parenterally is one given by a route other than the mouth (topical dosage forms are considered separately). The three main parenteral routes of drug administration are IV, IM, and SC, and in all cases administration is usually via a hollow needle. Injectable preparations are usually sterile solutions or suspensions of drug in water or other suitable physiologically acceptable vehicles. Volumes delivered can range from milliliter to liter quantities. The time of onset of action for IV administration is seconds, and for IM and SC injections is minutes. Depot injectable preparations achieve prolonged release and maintain therapeutic concentrations of drug throughout 25 days. The bioavailability of a drug, particularly from prolonged-release formulations, can be influenced by the location of the IM injection site. SC implants and pellets also achieve prolonged release of drug. A number of recombinant proteins and peptides are orally inactive and must be given by the parenteral route. Specialized dosage forms, usually for parenteral administration, are required for vaccines. In food animals, intramammary infusions and intravaginal devices are administered by the parenteral route.

Parenteral dosage forms and delivery systems include injectables (ie, solutions, suspensions, emulsions, and dry powders for reconstitution), intramammary infusions, intravaginal delivery systems, and implants. These dosage forms and delivery systems as well as the special considerations relating to intra-articular injections, recombinant proteins and peptides, and vaccines are discussed below. Also see the Drug Volume Calculator on this page to calculate the volume of a drug in ml to administer.

A solution for injection is a mixture of twoor more components that form a single phase that is homogeneous down to the molecular level. Water for injection is the most widely used solvent for parenteral formulations. However, a nonaqueous solvent or a mixed aqueous/nonaqueous solvent system may be necessary to stabilize drugs that are readily hydrolyzed by water or to improve solubility. A range of excipients may be included in parenteral solutions, including antioxidants, antimicrobial agents, buffers, chelating agents, inert gases, and substances to adjust tonicity. Antioxidants maintain product stability by being preferentially oxidized over the shelf life of the product. Antimicrobial preservatives inhibit the growth of any microbes accidentally introduced when doses are being withdrawn from multiple-dose bottles, and they act as adjuncts in aseptic processing of products. Buffers are necessary to maintain both solubility of the active ingredient and stability of the product. Chelating agents are added to complex and thereby inactivate metals, including copper, iron, and zinc, which generally catalyze oxidative degradation of drugs. Inert gases are used to displace the air in solutions and enhance product integrity of oxygen-sensitive drugs. Isotonicity of the formulation is achieved by including a tonicity-adjusting agent. Failing to adjust the tonicity of the solution can result in thehemolysis or crenation of erythrocytes when hypotonic or hypertonic solutions, respectively, are given IV in quantities >100 mL. Injectable formulations must be sterile and free of pyrogens. Pyrogenic substances are primarily lipid polysaccharides derived from microorganisms, with those produced by gram-negative bacilli generally being most potent. Injectable solutions are very commonly used, and aqueous solutions given IM result in immediate drug absorption, provided precipitation at the injection site does not occur.

A suspension for injection consists of insoluble solid particles dispersed in a liquid medium, with the solid particles accounting for 0.5%30% of the suspension. The vehicle may be aqueous, oil, or both. Caking of injectable suspensions is minimized through the production of flocculated systems, comprising clusters of particles (flocs) held together in a loose, open structure. Excipients in injectable suspensions include antimicrobial preservatives, surfactants, dispersing or suspending agents, and buffers. Surfactants wet the suspended powders and provide acceptable syringeability while suspending agents modify the viscosity of the formulation. The ease of injection and the availability of the drug in depot therapy are affected by the viscosity of the suspension and the particle size of the suspended drug. These systems afford enhanced stability to active ingredients that are prone to hydrolysis in aqueous solutions. Injectable suspensions are commonly used. Compared with that of injectable solutions, the rate of drug absorption of injectable suspensions is prolonged, because additional time is required for disintegration and dissolution of the suspended drug particles. The slower release of drug from an oily suspension compared with that of an aqueous suspension is attributed to the additional time taken by drug particles suspended in an oil depot to reach the oil/water boundary and become wetted before dissolving in tissue fluids.

An emulsion for injection is a heterogeneous dispersion of one immiscible liquid in another; it relies on an emulsifying agent for stability. Parenteral emulsions are rare, because it is seldom necessary to achieve an emulsion for drug administration. Untoward physiologic effects after IV administration may occur, including emboli in blood vessels if the droplets are >1 m in diameter. Formulation options for injectable emulsions are also severely restricted, because suitable stabilizers and emulsifiers are very limited. Examples of parenteral emulsions include oil-in-water, sustained-release depot preparations (given IM), and water-in-oil emulsions of allergenic extracts (given SC).

A dry powder for parenteral administration is reconstituted as a solution or as a suspension immediately before injection. The principal advantage of this dosage form is that it overcomes the problem of instability in solution. Proteins and other materials that are extremely heat sensitive cannot be dried in pharmaceutical driers. Rather, freeze-drying, or lyophilization, is used to produce a porous powder that reconstitutes readily.

Intramammary infusion products to treat mastitis are available for lactating and nonlactating (dry) cows. Lactating cow intramammary infusions should demonstrate fast and even distribution of the drug and a low degree of binding to udder tissue. These properties result in lower concentrations of drug residues in the milk. In contrast, it is desirable for nonlactating cow formulations to demonstrate prolonged drug release and a high degree of binding to mammary secretions and udder tissues. Particle size is particularly important, because it affects both the rate of release of the active ingredient and irritancy to the udder tissue. Drug particle size in nonlactating intramammary formulations is usually smaller than in those for lactating cows, which is critical to reduce irritancy during prolonged retention inthe udder. Thickening agents are added to modify the rate of release of the suspended particles from oil formulations, and antioxidants are commonly incorporated to prevent rancidity. Mastitis infusion products are often terminally sterilized by irradiation.

Intravaginal delivery systems include controlled internal drug-release (CIDR) devices, progesterone-releasing intravaginal devices (PRIDs), and vaginal sponges. These systems are used for estrus synchronization in sheep, goats, and cattle. Silicone is used in the manufacture of the T-shaped CIDR device and the coil-shaped PRID, whereas intravaginal sponges are made from polyurethane. The active ingredients in these systems are synthetic or natural hormones such as progesterone, methylacetoxy progesterone, fluorogestone acetate, or estradiol benzoate. An applicator consisting of a speculum and a separate plunger is used to insert sponges into the vaginal cavities of sheep and goats, and PRIDs into the vaginal cavities of cattle. A different type of applicator is used to insert CIDR devices into the vaginal cavities of sheep, goats, and cattle. Retention in the vagina depends on either the wings (CIDR device) or the entire device (sponges and PRIDs) expanding. With all three devices, gentle pressure is exerted on the vaginal wall. Retention of the device is >95%.

Most implants used in veterinary medicine are compressed tablets or dispersed matrix systems in which the drug is uniformly dispersed within a nondegradable polymer. Drug release from dispersed matrix systems involves dissolution of the drug into the polymer, followed by diffusion of the drug through the polymer and partitioning from the surface of the polymer into the surrounding aqueous environment. Implants are available to increase weight gain and feed conversion efficiency in food animals. These implants are typically prepared in a manner similar to tablets. One controlled-release implant consists of a cylindrical core of silicone, surrounded by an outer layer of estradiol-loaded silicone. A range of implants is available to enhance reproductive performance in breeding animals. These include ear implants containing norgestomet dispersed in polyethylene methacrylate or silicone,a biocompatible tablet implant containing deslorelin (a GnRH agonist) for use in mares that does not require removal, and a sustained-release pellet of melatonin, which is implanted in the ear of ewes to enhance breeding performance. Testosterone pellets are available to implant in the ears of wethers at doses of 70100 mg every 3 mo for the prevention of ulcerative posthitis.

The dosage forms used in intra-articular administration are sterile aqueous solutions. In horses, the two most common reasons for intra-articular injections are to anesthetize or "block" a joint during a lameness examination and to treat noninfectious inflammatory joint diseases such as synovitis and capsulitis. Drugs, including glucocorticoids, pentosan polysulfate sodium, and hyaluronic acid, are administered intra-articularly in inflammatory joint disease. The intra-articular administration of glucocorticoids avoids the adverse effects associated with large systemic doses. In dogs, hyaluronate sodium is administered by intra-articular injection for adjunctive treatment of synovitis.

Recombinant proteins and peptides are used in some countries to increase feed conversion efficiency and milk production in cattle (bovine growth hormone), increase feed conversion efficiency and produce leaner carcasses in pigs (porcine growth hormone), for the chemical shearing of sheep (epidermal growth factor), to reduce the incidence of skeletal weaknesses leading to leg injuries in horses (equine growth hormone), and for other uses. Recombinant proteins and peptides have been formulated as solutions, lyophilized powders, implants, and microparticles. The chemical and physical instability of recombinant proteins and peptides is a special consideration during formulation development. The major causes of chemical instability are proteolysis, deamidation, oxidation, and racemization. Causes of physical instability are aggregation, precipitation, denaturation, and adsorption tosurfaces. A range of strategies has been reported to stabilize formulations containing recombinant proteins and peptides, including the choice of carrier vehicle (eg, oleaginous vehicles), the use of lyophilization excipients, the use of stabilizers such as sugars and detergents, chemical modification of the proteins and peptides, and the use of site-directed mutagenesis to synthesize more stable proteins.

The organisms in live vaccines are subjected to freeze drying and, less commonly, to deep freezing at or below 70C. To maintain the viability of organisms under these conditions, formulations include complex mixtures of proteins, peptides or amino acids, sugars, and mineral salts. The viability of organisms is additionally protected using stabilizers such as lactose or other saccharides, skim milk, and serum.

Formulations used for inactivated and subunit vaccines consist of antigen(s), adjuvants, stabilizers, and preservatives (in the case of multiple-dose products). Inactivating agents such as phenol, thiomersal, and formaldehyde are used to kill the virus or bacteria without destroying the critical integrity of the antigens necessary to induce a protective immune response. Adjuvants enhance the immunogenicity of antigens by stimulating the immune system and prolonging antigen release. In this respect, aluminum hydroxide, aluminum phosphate, and oil emulsions are generally preferred to confer antibody-mediated immunity, whereas saponin, quil A, and immunity-stimulating complexes are preferred to confer cell-mediated immunity.

Plasmid DNA vectors have been used to express antigens in vivo to generate immune responses. Two delivery systems for DNA vaccines have been reported. In one system, the segment of DNA is coated with gold and administered to the patient using a gene gun. The other delivery system uses a viral vector or plasmid to carry the DNA segment into the patient.

The topical route of administration is used for local treatment of skin, control of external and internal parasites, and transdermal delivery of therapeutic agents. Drugs applied to the skin for local effect include antiseptics, antifungals, anti-inflammatory agents, and skin emollients. The rate of drug release from ointments, creams, and pastes is principally determined by the semisolid base used. In dogs and cats, an extensive range of topical formulations is used in the control of fleas, lice, mites, and ticks. These include insecticidal and acaracidal soaps, foams, shampoos, sprays, and rinses. Also available are topical delivery systems such as spot-on formulations and flea and tick collars and medallions. In food animals, a diverse range of topical dosage forms and delivery systems are used to control external parasites. For example, most pour-on formulations, plunge and shower dip concentrates, and jetting fluids are suspension concentrates or emulsifiable concentrates. In addition, many pour-on formulations display endectocidal activity in cattle. The efficacious systemic concentrations attained with these preparations result from the animal's licking behavior and, to a lesser extent, percutaneous absorption of the active ingredient. Numerous methods are used to apply parasiticides to farm animals (see below). A special consideration relating to the use of topical dosage forms is the potential for residues in wool and mohair to occur. The topical route of administration is also used to deliver therapeutic agents systemically. Transdermal patches, for instance, are used to deliver analgesics to the systemic circulation.

The topical dosage forms available to treat animals include solids (dusting powders), semisolids (creams, ointments, pastes, and gels), and liquids (solutions, suspension concentrates, suspoemulsions, emulsifiable concentrates, paints, and tinctures). These dosage forms as well as the specialized topical dosage forms and delivery systems for transdermal drug delivery and parasite control are discussed below.

A dusting powder is a finely divided insoluble powder containing ingredients such as talc, zinc oxide, or starch. Coarse powders often have a gritty feel, whereas powders containing particles that are <20 m in all dimensions have a smooth feel. Some dusting powders absorb moisture, which discourages bacterial growth. Others are used for their lubricant properties. The use of dusting powders is indicated on skin folds and contraindicated on wet surfaces, because caking is likely to result.

A cream is a semisolid emulsion formulated for application to the skin or mucous membranes. Droplet diameter in topical emulsions generally ranges from 0.1100 m. Cream emulsions are most commonly oil-in-water but may be water-in-oil. The former readily rub into the skin (hence the term vanishing cream) and are removed by licking and washing. By comparison, water-in-oil emulsions are emollient and cleansing. Water-in-oil emulsions are also less greasy and spread more readily than ointments, and they soothe inflamed skin as a consequence of the water in the formulation evaporating.

An ointment is a greasy, semisolid preparation that contains dissolved or dispersed drug. A range of ointment bases is used, including hydrocarbons, vegetable oils, silicones, absorption bases consisting of a mixture of hydrocarbons and lanolin, emulsifying bases consisting of a mixture of hydrocarbons and an emulsifying agent, and water-soluble bases. Ointment bases influence topical drug bioavailability via twomechanisms. First, their occlusive properties are responsible for hydrating the stratum corneum, which enhances the flux of drug across the skin. Second, they affect drug dissolution within the ointment and drug partitioning from the ointment into the skin. Ointments are effective emollients because of their occlusive nature. They are indicated for chronic, dry lesions and contraindicated in exudative lesions.

A paste for topical use is a stiff preparation containing a high proportion of finely powdered solids such as starch, zinc oxide, calcium carbonate, and talc. Pastes are less greasy than ointments, because much of the fluid hydrocarbon fraction is absorbed onto the solid particles; they are also less occlusive than ointments. Pastes are indicated for ulcerated lesions.

A gel is a nongreasy, semisolid, aqueous solution. The semisolid properties are due to a polymer imparting a continuous structure to the hydrophilic liquid. The polymers used include natural gums such as tragacanth, pectin, and agar; semisynthetic materials such as methylcellulose, hydroxymethylcellulose, and carboxymethylcellulose; and synthetic polymers such as carbopol. Medicaments are generally well released from gels, which are easily washed off on account of their water miscibility.

A solution for topical use is a mixture of two or more components that form a single phase down to the molecular level. Topical solutions include eye drops, ear drops, and lotions. Eye drops are sterile liquids that contain a range of drugs, including local anesthetics, antibiotics, anti-inflammatory agents, and drugs acting on the autonomic nervous system of the eye. They are instilled onto the eyeball or within the conjunctival sac. Ear drops are solutions of drugs such as antibiotics, insecticides, or anti-inflammatory agents. The vehicle may be water, glycerol, propylene glycol, or alcohol/water mixtures. They are applied to the external auditory canal.

A lotion is usually an aqueous solution (or suspension) for application to inflamed, ulcerated skin. Lotions cool the skin by evaporation of solvents, leaving a film of dry powder. Lotions are suitable for use on hairy areas and for lesions with minor exudation and ulceration.

A suspension concentrate for topical use is a mixture of insoluble, solid active ingredients, which are typically at high concentrations, in water or oil. Suspension concentrate formulations are generally water-based; the water-insoluble active ingredients and inert ingredients are of very small particle size (0.15 m). Other formulation additives include suspending agents, surfactants, and other excipients toensure the production of a shelf-stable, pourable product. Surfactants wet, disperse, and stabilize the solid particles in the continuous phase, prevent flocculation, and prevent changes in particle size. Thickening agents are included to increase the viscosity of the formulation, thereby overcoming sedimentation of the suspended particles and affording good longterm stability. Suspension concentrates are used topically as pour-ons, plunge and shower dip concentrates, and jetting fluids.

A suspoemulsion combines the elements of an emulsion and a suspension, allowing active ingredients with widely varying physical properties to be formulated in a single product. Typically, a suspoemulsion contains one or more solvent-soluble active ingredients in an emulsion phase, combined with one or more low solubility active ingredients in a continuous aqueous suspension phase.

After dilution, an emulsifiable concentrate for topical use produces a two-phase system involving two immiscible liquids, a dispersed phase, consisting of fine oil droplets ranging in size from 0.5 m to several hundred microns, and a continuous phase. Addition of an emulsifiable concentrate formulation to water results in the formation of an emulsion, which relies on surface-active agents concentrating at the oil/water interface. Active ingredients that are soluble in water-immiscible organic solvents are frequently formulated as emulsifiable concentrates. The flocculation of oil droplets in emulsifiable concentrate formulations leads to a layer of cream that can be readily dispersed by mild agitation, whereas the coalescence of droplets leads to the inversion or breaking of the emulsion. Water with a high content of Ca2+ and/or Mg2+ reacts with anionic surfactants in the emulsifiable concentrate formulation; this affects both spontaneity of emulsification and stability. Zinc sulfate, used as a dip additive to minimize the spread of dermatophilosis in sheep, also adversely affects emulsions.

A flank paint comprises an antifoaming agent such as a detergent or mineral oil and is used to prevent pasture bloating in cattle. A flank paint is applied to the flanks of animals, from where it is licked off and ingested. Bloat, or ruminal tympany, refers to excessive accumulation of gas in the rumen. Frothy bloat commonly develops in cattle on pasture, particularly those grazing lush, leguminous pastures. Frothing of rumen ingesta occurs when the viscosity of the fluid is increased. Froth obstructs the cardia of the stomach, preventing the eructation of excessive gas produced in the rumen. Antifoaming agents reduce the stability of the froth by lowering the viscosity of the fluid ingesta.

A tincture for topical application uses a vehicle containing 15%80% alcohol, requiring the preparation to be tightly stoppered and not exposed to high temperatures. In addition to alcohol, tinctures may contain cosolvents, stabilizers, and solubilizers. Iodine tincture is a topical anti-infective that contains 44%50% alcohol. The reddish brown color of iodine tincture produces skin staining that delineates treated skin. Friar's balsam is compound benzoin tincture and is used to protect and toughen ulcerated or fissured skin.

A transdermal delivery gel consists of a vehicle, most commonly pluronic lecithin organogel (PLO gel), which delivers drug via the transdermal route to the bloodstream. The micellar composition of PLO gel enhances skin penetration of the pharmaceutical agent present in the formulation. PLO gel is generally well tolerated and is nontoxic if ingested. However, not all drugs are suitable for transdermal application, and there are relatively few studies of the bioavailability of drugs from compounded transdermal gels. Transdermal gels are used to deliver drugs to treat several diseases in dogs and cats, including undesirable behavior, cardiac disease, and hyperthyroidism. The dose is applied to the inner surface of the pinnae, thereby offering ease of administration, especially in cats.

A transdermal delivery patch typically consists of a drug incorporated into a reservoir, a protective backing layer, a rate-limiting release membrane, and an adhesive layer to secure the patch to the skin. The physicochemical properties of a drug suitable for transdermal delivery ideally include low molecular weight (<500 daltons), high potency, water solubility (to facilitate movement of the drug out of the reservoir and to allow passage through the epidermal and dermal layers of the skin), and lipid solubility (to permit penetration of the stratum corneum of the skin). Fentanyl, a synthetic opioid agonist, is delivered by transdermal patch in dogs, cats, and horses.

The control of internal and external parasites of companion and food-producing animals has led to development of specialized dosage forms, delivery systems, and application methods unique to veterinary medicine.

A spot-on formulation is a solution of active ingredient(s) that typically contains a cosolvent and a spreading agent. The active ingredients in spot-on products for flea, GI parasite, or heartworm control in dogs and cats include fipronil, imidacloprid, selamectin, pyriproxyfen, ivermectin, and moxidectin. Spot-on formulations are also available to control lice in cattle. The physicochemical properties of the active ingredient(s) are important determinants of topical or transdermal behavior. Topical activity against ectoparasites depends to some extent on the active ingredient spreading, mixing with the sebum coating the skin and hair, and forming depots in the pilosebaceous units. The mechanism of percutaneous drug absorption varies between species and is not completely understood. However, low molecular weight and a high lipid/water partition coefficient tend to favor passage of the drug through the skin.

Backliner products for sheep consist of pour-on and spray-on formulations for the control of lice and sheep blowflies. Sheep lousicides include synthetic pyrethroids, organophosphates, and insect growth regulators. These products are formulated for pour-on application within 24 hr after shearing (ie, off-shears) or spray-on application (in short-wool sheep with wool growth <6wk, and in long-wool sheep with wool growth >6 wk). Their efficacy against lice depends on topical activity and not on percutaneous absorption of the active ingredient into the bloodstream. Translocation of the pesticide from the application site to remote sites at concentrations lethal to lice is critical to the efficacy of these products and, in the case of pour-on applications, is facilitated by the increased secretion of wool grease that occurs at shearing.

The active ingredients in sheep blowfly products include insect growth regulators, synthetic pyrethroids, and organophosphates. After their topical application, sheep blowfly larvicides form follicular depots and subsequently translocate as a coating on new wool growing out of the follicles.

Hand-jetting of long-wool sheep (wool growth >6 wk) is done to control lice, keds, mites, and sheep blowflies. The pesticides used include rotenone, synthetic pyrethroids, organophosphates, insect growth regulators, and macrocyclic lactones. Hand-jetting involves the use of a handpiece (or wand) to rake a pesticide solution into the wool along the dorsal midline and sometimes into the breech, crutch, and poll. The solution is applied under pressure and penetrates to the skin.

Some pour-on products on the market are formulated to deliver an active ingredient percutaneously. The macrocyclic lactones ivermectin, moxidectin, doramectin, and eprinomectin are formulated as pour-on preparations for application to cattle. These formulations are usually solutions or emulsifiable concentrates for dilution with water before use. The principal route of percutaneous absorption for most drugs in people is the intercellular pathway, making the intercellular lipid matrix the primary barrier to absorption. However, this may not be the case in species in which the emulsifying properties of skin secretions and the large numbers of follicles and glands per unit surface area must be considered (eg, cattleand sheep). Ionized solutes, for example, are reported to cross the skin of animals via shunt pathways (sweat ducts, follicles). Pour-on products are formulated to spread without run-off when applied to the skin and to be resistant to rain. The formulation also facilitates the partitioning of the drug out of the vehicle and into the skin and transport of the drug across the skin. The control of these processes is critical, because some drug is required to remain at the skin if the drug is to be active against external parasites that are not blood sucking. In addition, too rapid passage of drug through the skin may result in unacceptable chemical residues in tissues or milk.

The plunge dipping of sheep and cattle for external parasites requires a dipping vat, which may be a portable unit or a permanent in-ground structure shielded from direct sunlight by roofing. A draining pen located at the exit of the vat allows dip wash that drains off treated animals to return to the vat. Dip chemicals are usually formulated as aqueous solutions, emulsifiable concentrates, or suspension concentrates, all of which are diluted with water before use. The high costs associated with plunge dipping relate principally to the costs of chemicals for charging large vats, labor, and the disposal of the hazardous wastes. Plunge dips must be managed properly and the pesticide maintained at the concentration recommended by the manufacturer. Dipping of sheep and cattle is associated with stripping of the active ingredient from the dip wash (eg, pesticide loss from the dip wash occurring at a greater rate than water loss) and is categorized as mechanical or chemical. In the case of sheep, mechanical stripping results from the fleece acting as a sieve toward the active ingredient, with the degree of filtration being primarily determined by particle size. Chemical stripping is due to the preferential absorption of pesticide by the fleece. To counteract stripping, a complex dip management regimen that involves reinforcement and topping-up is used. Reinforcement refers to the addition of undiluted chemical product to the dip without the addition of water, whereas topping-up refers to the addition of water and undiluted chemical product to the dip vat to return the volume to the starting level. Proper dip management also minimizes contamination of the dip with organic matter. This requires that the race leading to the vat is constructed of concrete or slats to remove dirt from the animals feet and that animals be held in a yard overnight before dipping, during which time they are offered water but no feed.

Hand spraying generally results in uneven coverage of animals and is considered an inefficient method of application. By comparison, recirculating and nonrecirculating spray races facilitate whole body spraying and wet cattle to the skin. The situation with sheep is differentthe very short contact time in a spray race limits the uptake of insecticide, which means the fleece seldom becomes saturated. Because of this, spray races should be used as an adjunct to shower or plunge dipping of sheep.

Shower dips are less labor intensive than plunge dips and are cheaper to operate. A typical shower dip consists of a sump containing the dip wash, a pump, and a showering pen constructed with a concrete floor and fitted with rotating and fixed nozzles. There are two types of shower dips: a conventional shower dip in which the sump volume is periodically maintained by adding fresh dip wash, and a constant replenishment shower dip in which a small-volume sump is continually filled from a large-volume supply tank to maintain dip levels. Proper dip management requires attention to the factors described above for plunge dipping. In addition, all equipment must be functioning properly for the fleece to become saturated. Sheep should not be dipped (by either the plunge or shower method) until shearing wounds have healed to avoid clostridial infections or caseous lymphadenitis caused by Corynebacterium pseudotuberculosis. Moreover, the correct use of bacteriostats is recommended to prevent post-dipping lameness caused by Erysipelothrix insidiosa.

Insecticidal collars are plasticized polymer resins impregnated with an active ingredient. Collars for the control of ticks and fleas on dogs and cats release the active ingredient as a vapor, a dust, or a liquid,depending on the physicochemical properties of the chemical. Volatile liquid insecticides such as dichlorvos or naled are used in vapor-release collars. The insecticide distributes through the collar matrix as a vapor before being released. Powdered insecticides such as phosmet, stirofos, carbaryl, and propoxur are used in dust-release collars. Translocation of the active ingredient within the collar matrix leads to deposits forming at the surface; distribution of the insecticide to the animal depends on the animal's physical activity. Nonvolatile liquid insecticides such as chlorfenvinphos or diazinon are used in liquid-release collars. The active ingredient distributes as a liquid in the collar matrix and to the surface, where it is released. The animals activity plus the dissolution of lipophilic insecticides in skin secretions are important factors in translocation of the insecticide from the collar to the animal.

Two types of insecticide-releasing ear tags to control flies on cattle are available. One is constructed from a polymer that provides structural support and acts as a release rate-controlling matrix. The other is a membrane-based ear tag that consists of an insecticidal reservoir with arelatively impermeable backing on one side and a rate-controlling membrane on the other. Both types rely on the animals ear and head movements and grooming to transfer insecticide from the surface of the ear tag to the animals skin or to other animals.

Back rubbers typically consist of burlap supported across lanes, gateways, or areas where cattle congregate. Back rubbers arecharged by soaking thoroughly in oil-containing pesticide, typically a synthetic pyrethroid, an organophosphate, or a combination of the two. The oil retards evaporation of the insecticide and enhances adherence to the animals coat.

Dust bags facilitate the self-treatment of cattle to control flies and lice. They areconstructed of an inner porous bag containing the active ingredient, which is commonly a synthetic pyrethroid or an organophosphate, and an outer weatherproof skirt. Dust bags are hung in lanes orgateways so that passing cattle brush against them and receive a topical application of pesticide.

Inhalational anesthetics are critical in management of anesthesia. Currently, enflurane, halothane, isoflurane, methoxyflurane, and nitrous oxide are the most commonly used inhaled anesthetic agents. These agents are usually delivered to animals in a carrier gas that includes oxygen, using an anesthetic machine fitted with one or more vaporizers and a patient breathing circuit.

Inhalational therapy of airway disease is used to deliver high concentrations of drugs to the lungs while avoiding or minimizing systemic adverse effects. To be delivered into the airways, a drug must be presented as an aerosol, either as solid particles or liquid droplets in air. Particle or droplet size largely determines the extent to which the drug penetrates the alveoli. Particles too small or too large for optimal delivery into alveolar sacs are either exhaled or deposited on larger bronchial airways. Compared with delivery by the oral or parenteral routes, the onset of pharmacologic action of inhaled agents is faster and the doses administered smaller, thereby reducing the potential incidence of adverse systemic effects. The delivery systems used for inhalational therapy of airway disease in animals are nebulizers and metered-dose inhalers. In the poultry industry, inhalation of aerosolized vaccines is a common way to immunize flocks of birds.

Merck & Co., Inc., Kenilworth, NJ, USAis a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Manual outside of North America.

pellet making systems for farms - elf pellet mills for sale - north america

pellet making systems for farms - elf pellet mills for sale - north america

ELF has extensive knowledge of pelleting straight cereal grasses and other grass types with or without mixed components. Also we have a lot of experience with seed cleaning (screenings) waste as feed. These mixtures and our many years of experience from both North America and Europe are critical to our success.

Poultry litter pellets made in a 3-mm size crumble are ideal for spreading on fields or bagging as a retail product. Other manures such as horse, cattle, sheep, etc. can be made into high-value fertilizer for you your litter pelleting needs. Learn more about Fertilizer Pellets here.

You can put 100% wheat-straw bedding through our patented system. First, the straw is put through a hammer mill and then pelletized to a soft bedding pellet that has a cracked surface to absorb moisture very quickly. When cereal straws are pelletized in this way, they are 3 x more absorbent than standard straw bedding and twice as absorbent as shavings or sawdust.

High-quality pelleted feed is important to maximize the growth rate and feed efficiency of many types of livestock. From feed for fowl such as chickens and ducks to feed for rabbits, sheep, goats, cattle, and equines, our compact systems give you control over what goes into the pellets and what size pellets are made.

AMSs (or robot feeders) are fast becoming the choice of many large dairy farmers. Flexibility in the workday, decreased labor, and more frequent milking for high-producing cows are the most prominent advantages of robotic milking. One disadvantage is the cost of quality pellet feed. Our systems give you the advantage of producing a custom feed to suit your AMS system that is much cheaper than buying pre-made pellets. Many reports show that creating custom, high-value feeds increases the amounts of milkings through AMS units.

pellet mills for sale - canada, usa, north america pellet making systems

pellet mills for sale - canada, usa, north america pellet making systems

With over 24 years of combined experience in the biomass, wood, and farming industries ELF Systems is proud to bring to the market, specialized grinding and pellet making systems designed for the smaller operator who wants absolute quality.

We understand that buying a piece of quality equipment is a large investment and comes with numerous anxieties and concerns, not only of the equipment but of the process itself. Thats why we offer a 4 stage peace of mind guarantee for each customer.

We offer peace of mind, with modern and innovative designs. Our systems are heavy duty, built to the highest quality, using the best materials available at an affordable price. Our HB lines of pellet mills have low cost of production, with very little downtime for the operator. Our models include

We manufacture our systems in the heart of the Czech Republic, just outside of Prague. We welcome tours of our facilities so you can have peace of mind that the equipment is made with the highest of quality. We are leading suppliers of turnkey industrial-grade small grinding and pellet making machines in the USA & North America. Our Pellet Mills utilize the latest machinery, designed by us built by us! We guarantee our equipment to work and offer full training via internet or even in person.

Make your own pellets from just about any material alfalfa, hops, grass, wood, hemp, municipal waste (MSW), algae, biomass etc for use as feed, fuel, fertilizer, litter or anything you require. Accomplish this efficiently with our custom-built turnkey specialized mini pellet plants. We offer systems that handle everything from grinding to packaging. Our turnkey pellet mills are suitable for 100kg up to 300kg per hour (depending on model and material)

All of our equipment is designed with efficiency and longevity in mind, also our main goal is to make our clients operations profitable and sustainable for years to come. We deliver you quality turn key systems that will run for years.

small poultry feed pellet mill plant for sale at factory price

small poultry feed pellet mill plant for sale at factory price

Due to increased technology, poultry feed pellet mill is among the new machines in the market. They are making it easier to make pellets for a various variety of animals like fish, sheep, cattle, poultry, rabbit, chicken, duck, cheese, geese among others. The machine is able to make pellets of a diameter ranging from 2mm to 8mm. It has a capacity of producing 600kg/hour to 1000kg/hour. This means you can control the speed of production depending on the demand in the market. The machine is a great boost to small-scale farmers in the market since they can invest in the small amount of money they have with the machine.

There are two types of the poultry feed mill machinery for sale. STLP 300 and STLP 400 feed pellet machines differ slightly when it comes to grinding, conveying, pelletizing, mixing and cooling but produce the same material. The cost of this poultry feed mill plant is about $10,000~$25,000. Just feel free to contact us and inquiry for detailed quotaion.

GEMCO is a reliable feed pellet machine supplier in China, with decades of experiences in livestock and poultry feed manufacturing process.This small feed plant is one of our hot sell equipment for small poultry feed making factories around the world espacially in India. If you want to buy chicken feed pellet mill for starting your own mini poultry feed factory, it should be your best choice! Whenever you are interested in our equipments for making feed pellets, don't hesitate to get in touch!

Poultry feed pellet mill as explained earlier is a small and less complicated machine. This makes the processing of the pellets a bit easier to comprehend. The initial process is to bring the material for making the pellets. These includes soya bean meal, maize meal, vitamin among others.

This is the first step to ensuring all the large grains are crushed into powder forms. The pellet mill has a grinding machine that is specifically for the crushing purposes. Maize meals, broomcorn, wheat, beans, oilseed meal, soya bean meal may be in large grains and hence must pass the process. They are taken to the crushing machine where they are crushed into fine powder. Without this process, it might be next to impossible to make pellets.

This is where all the ingredients are mixed. The mixing machine is known as 9HLP vertical mixing machine. It has a large barrel where all the ingredients are put in different proportions. With the help of the machines, the powder is mixed in different proportions to form one mixture which is known as feed mesh.

The pelletizing system incorporates the pellet mill for poultry feed. This is meant to press the feed mesh and form pellets. The machine used here is the ZLSP 300 and ZSLSP 400. It is able to make the pellets into uniform sizes. These includes the same diameter and length. This is to ensure that the poultry feed pellet mill produces the required sizes for different animals to ensure that it provides what is required and also avoid wastage during feeding. ZLSP series feed pellet machine is widely used insmall chicken feed production lineand small cattle feed pellet mill.

After crushing, mixing and pelletizing the final process is cooling. The machine used here is the KLN series counter flow type cooler. The machine is small in size and convenient when transporting and installing. At the pelleting system, the pellets tend to produce heat which ranges from 70 to 85 degrees. This heat must be reduced to room temperature to meet the storage requirement. Without cooling process, the hot pellets would produce mildew resulting to damage of the pellets. With a cooling fan in place, the pellets pass through the cooling area and their temperature is reduced to harmless levels. The pellets are then packed and stored in a cool dry place.

used pellet mills for sale. sinodec equipment & more | machinio

used pellet mills for sale. sinodec equipment & more | machinio

Product Description Specification Packing & Delivery Company Profile 00:00 02:00 FAQ Recommended by seller Factory dry dog food dispenser high quality mini puppy pet machinery petfood machine $1,000.00 - $2,000.0...

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Pelletizing mill / Granulating machine for wood pellets Descriptions: wood pellets mill is specially designed for biomass industrial production of wood pellets, the raw materials are easy to obtain, like groundnu...

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Pelletizing Mill / Granulating Machine Briquetteing Machine for Wood Pellets Descriptions: wood pellets mill is specially designed for biomass industrial production of wood pellets, the raw materials are easy to ...

Pelletizing Mill / Granulating Machine Briquetteing Machine for Wood Pellets Descriptions: wood pellets mill is specially designed for biomass industrial production of wood pellets, the raw materials are easy to ...

Product description Overview animal feed pellet machine special for animal feed pellet machine,60-80kg/h,match single phase motor 2.2kw Packing and shipping Packing details: 1. We pack Heli chengdu agricultural m...

Pelletizing Mill / Granulating Machine Briquetteing Machine for Wood Pellets Descriptions: wood pellets mill is specially designed for biomass industrial production of wood pellets, the raw materials are easy to ...

Pelletizing Mill / Granulating Machine Briquetteing Machine for Wood Pellets Descriptions: wood pellets mill is specially designed for biomass industrial production of wood pellets, the raw materials are easy to ...

Pelletizing Mill / Granulating Machine Briquetteing Machine for Wood Pellets Descriptions: wood pellets mill is specially designed for biomass industrial production of wood pellets, the raw materials are easy to ...

Pelletizing mill / Granulating machine for wood pellets Descriptions: wood pellets mill is specially designed for biomass industrial production of wood pellets, the raw materials are easy to obtain, like groundnu...

biomass & wood pellet making machines | pellet mill solutions

biomass & wood pellet making machines | pellet mill solutions

Our knowledgeable team is here to help you through the process of finding the pellet mill for your needs. We started by narrowing the choices down to quality pellet mills that are built in America.We have products that are able to produce pellets for wood fuel, feed, animal bedding, fertilizer and more. We listen to what your production and product needs are. We then recommend the right biomass pelletizing solution that is right for you.We are happy to work with universities and technical schools, agricultural, commercial, government and private parties.

agricon - pelleting and pelletizing machine manufacturing solutions

agricon - pelleting and pelletizing machine manufacturing solutions

Agricon is the world leader in small-scale pellet machine manufacturing for agriculture and biomass pelletizing. Our range includes tractor-driven, single phase and three phase pelletizers and full production plant solutions with spares, backup and support.

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pellet mill plans for animal feed pellet making solutions

pellet mill plans for animal feed pellet making solutions

It can make feed pellets with different diameters for poultry and livestock. We have three types feed pellet machines for your choice. Electric Flat Die Feed Pellet Mill is your inevitable choice for making your own feed pellets. Diesel Flat Die Feed Pellet Mill is especially favored by small farm holders and poultry breeders. Ring Die Feed Pellet Mill is more efficient and suitable for industrial poultry feed pellets production, large farms or feed pellets factory.

The feed pellet production line can be used to make feed for rabbit, duck, cattle, chicken, sheep, pigs, pigeon, etc. The whole production line can be controlled by the automatic PLC control system. The complete poultry feed pellet line include the following steps. Raw Materials Crushing Mixing Pelletizing Feed Pellet Cooling Crushing Screening and Grading Packing

Floating fish feed extruder is popular in modern fish farming industry. It can make floating feed pellets for all kinds of fish, shrimp, crab, etc. Dry Type Fish Feed Extruder is really cost-effective to make your own fish feed pellets, easy to use and operate. Wet Type Fish Feed Extruder can produce better quality fish feed in larger scale, also ideal for making pet food for dogs, cats, etc.

The line is special designed for makinghigh-grade floating fish feed pellets from corn, maize, grass, protein, molasses, etc. It is the complete procedure of feed pellet production with super automation control and high production efficiency. The fish feed making process is as follows. Crushing Mixing Extruding Pellet Drying Oil Spraying Pellet Cooling Pellet Packaging

It is an ideal pelletizing machine for large-scale high quality aquatic feed pellet production. The finished feed pellets have smooth surface and easy to digest. With advanced technology and outstanding advantages, aquatic feed pellet mill is widely adopted in aquaculture.

cattle feed pellet mill-how to make cattle feed

cattle feed pellet mill-how to make cattle feed

Cattle feed pellet is an all-in-one pellet form feed made by feed pellet mill through great pressure. It is a kind of feed that is not only for oxen, cows, cattle but also for sheep, and goat reared for their milk and meat. It contains protein, minerals and other nutrients which are useful for beef and milk production and survival of the animals.

Cattle feed pellets can be prepared from oil cakes, agro-residues such as peanut seedling, grass, maize straw, wheat straw, grain, wheat bran etc., flour mill by-products, cereals, molasses, and so on.

The major operations involved in the production of cattle feed pellets are: raw materials preparation, primary crushing, molasses mixing, fine crushing, pellet making and packaging(optional) Raw and auxiliary materials are first charged into silos and tanks where they are made ready for further processing. They are then processed by primary crusher. Crushed materials are further separated by means of a sieve, and then stored in the assorting tanks according to the kind of raw materials. The raw materials are then mixed by means of a feed mixer. In this process, fatty ingredients are added to the materials in order to raise the nutritional value of the feed. The feed obtained from the mixer is blended with molasses. Assorted animal feed that is crushed into fine particles is further formed into pellets by a cattle feed pellet mill.

Machinery and equipment required in the cattle feed pellet production line are as following. 1. Tank( or other containers ) for raw and auxiliary materials storage 2. Feed hammer mill(feed pellet grinder) for grinding the raw materials to feed powder. 3. Feed pellet blender( feed pellet mixing machine) used to mixing powdered materials to improve the uniformity of the ingredients. 4. Feed pellet mill(feed pelletizer) is the main equipment for making the cattle feed pellets. For cattle feed mill, we supply flat die feed pellet mill design better for home use and ring die feed pellet mill design for cattle feed factory. If you plan to buy a cattle feed pellet mill, you can tell us your capacity requirement, then our salesman will give you a good recommendation.

6. Feed pellet cooler is used to cool the hot and moisture feed pellets(if your production capacity per day is not so much, you will not need this pellet cooler, just dry the pellets in the sun is OK.) 7. Feed pellets screening and grading machine is used to remove the fines and grade the pellets, which is the preparation for packaging. 8. Feed pellet weighing and packaging machine is used to weigh and pack the pellets in the uniformity(If making cattle feed pellets for your own farm, you can choose to store the pellets in a dry container instead of buying a packing machine, while for an automatic feed pellet plant, the weight and packing machine is necessary.) 9. Other auxiliary machines( conveyor, lifter, etc. Usually used in an automatic cattle feed pellet line)

1. From a feed manufacturers perspective, the benefits of making feed pellets include decreased segregation of mixed feedstuffs, increased bulk density, reduced dustiness and improved handling characteristics. 2. For farmers making own cattle feed, will greatly save cost compared buying feed pellets from other manufacturers.

home - feed pellet mill manufacturer/expert in feed pelletizing solutions

home - feed pellet mill manufacturer/expert in feed pelletizing solutions

Wet Type Fish Feed Mill: Make high-grade aquatic feed pellets for fish, catfish, shrimps, crab etc. Ideal for making pet food for dogs, cats, etc. First choice of fish feed pellets manufacturers.

We are able to share our experience on a wide selection of products and give you useful suggestions for most suitable choice. Our machines are made from precision casting technology and strict quality control, thus ensuring long time service life.

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